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Home»Guides»Resident Evil Requiem: all combinations to open the safes
Resident Evil Requiem: all combinations to open the safes
Guides No Comments

Resident Evil Requiem: all combinations to open the safes

Adrián FuentesBy Adrián Fuentes27 February, 2026No Comments

Quick guide with the codes for each safe without gutting its contents.

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If you’re already making progress in Resident Evil Requiem, you’ll have noticed that several areas hide safes that can only be opened by entering the correct combination. Some hints are well-hidden and can be easily missed on the first playthrough.

To save you from having to scour every corridor repeatedly, we’ve got all the known combinations for you, organized by location. We won’t reveal what’s inside to avoid spoiling the surprises.

Safe Combinations in Resident Evil Requiem

Rhodes Hill Patient Center – West Wing (2nd floor)

  • Combination: 10 left, 80 right, 30 left

Rhodes Hill Patient Center – East Wing (1st floor)

  • Combination: 30 right, 10 left, 50 right

Rhodes Hill Patient Center – Basement

  • Combination: 60 right, 40 left, 80 right

ARK – Sterilization Room

  • Combination: 10 right, 90 left, 20 right

ARK – Control Room

  • Combination: 50 right, 60 left, 80 right

Raccoon City Police Station – Briefcase

  • Combination: R-R-R

Remember to enter the numbers in the exact correct order (left or right), as the system doesn’t allow for errors. If you’re aiming for 100% completion or just don’t want to leave anything behind, these combinations will save you a lot of time and work across all difficulty levels.

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This content has been automatically translated from the original material. Due to the nuances of machine translation, there may be slight differences. For the original version,click here.
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Adrián Fuentes
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Founder and editor of SoloXboxOne and Generación Xbox. He is also one of the owners of the GX Group, Samsung Universe and the Reflotes forum. Adrian has reviewed over 200 games on the web and has an average score of 85 according to Opencritic. Among his expertise as a writer and analyst, he has interviewed Microsoft personalities and participated in private gaming events.


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